San Antonio fire crews responded to a house fire in the 800 block of Alametos Street off Fresno late Thursday afternoon.
Firefighters from 10 trucks battled the blaze of the two-alarm fire that was first reported at around 4p.m.
The home's burglar bars made it difficult for crews to gain access to the home.
Two firefighters were injured with first and second-degree burns to ears, arms and neck.
No one was home at the time the fire broke out. The home itself is considered a total loss.