One person is dead after a major accident on the south side where two vehicles hit head-on.

A white 2000 Dodge Ram hit a black Ford Explorer SUV around 8:20 p.m. Saturday on Highway 16 near South Zarzamora Street.

Witnesses say that one of the vehicles lost a tire before the driver lost control. At least three people were trapped inside one of the vehicles.

AirLIFE was flown in to transport the patients. More than a dozen emergency crews were still on scene as of late Saturday night.

UPDATE: An earlier version of this story reported that two people had died and that both vehicles were pickup trucks.